Original paper
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Abstract
The microbial adaptive immune system CRISPR mediates defense against foreign genetic elements through two classes of RNA-guided nuclease effectors. Class 1 effectors utilize multi-protein complexes, whereas class 2 effectors rely on single-component effector proteins such as the well-characterized Cas9. Here, we report characterization of Cpf1, a putative class 2 CRISPR effector. We demonstrate that Cpf1 mediates robust DNA interference with...
Paper Details
Title
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Published Date
Oct 1, 2015
Journal
Volume
163
Issue
3
Pages
759 - 771
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History