Original paper

Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene

Volume: 58, Issue: 11, Pages: 2616 - 2623
Published: Aug 3, 2009
Abstract
In a genome-wide association scan, the rs738409 C>G single nucleotide polymorphism (SNP) in the patatin-like phospholipase 3 gene (PNPLA3) was strongly associated with increased liver fat but not with insulin resistance estimated from fasting values. We investigated whether the SNP determines liver fat independently of visceral adiposity and whether it may even play a role in protecting from insulin resistance.Liver fat was measured by (1)H...
Paper Details
Title
Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene
Published Date
Aug 3, 2009
Journal
Volume
58
Issue
11
Pages
2616 - 2623
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