Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon

The colonic microflora is involved in the pathogenesis of Crohn's disease (CD) but less than 30% of the microflora can be cultured. We investigated potential differences in the faecal microflora between patients with colonic CD in remission (n=9), patients with active colonic CD (n=8), and healthy volunteers (n=16) using culture independent techniques.Quantitative dot blot hybridisation with six radiolabelled 16S ribosomal ribonucleic acid...