The long-term effect of dietary supplementation with fish lipid concentrate on serum lipids, bleeding time, platelets and angina

The effect of a fish lipid concentrate rich in eicosapentaenoic acid was studied in 107 subjects for periods up to 2 years. Ninety-two had heart disease or hyper-lipidaemia and 15 had no history of heart disease. Serum triglyceride levels were rapidly reduced, cholesterol fell more slowly but high density lipoprotein (HDL) cholesterol was increased. Bleeding time increased significantly and the consumption of glyceryl trinitrate (GTN) tablets...