The prognostic value of stroma in pancreatic cancer in patients receiving adjuvant therapy

BackgroundPancreatic ductal adenocarcinoma (PDA) is comprised of a prominent desmoplastic stromal compartment and only 10–40% of the tumour consists of PDA cells. However, how stromal components should be assessed and how the characteristics of the stromal compartment determine clinical outcomes in PDA patients remain unknown.MethodA cohort of 66 consecutive patients who underwent pancreaticoduodenectomy and were primarily followed at Johns...