Original paper
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
Abstract
The BLAST programs are widely used tools for searching protein and DNA databases for sequence similarities. For protein comparisons, a variety of definitional, algorithmic and statistical refinements described here permits the execution time of the BLAST programs to be decreased substantially while enhancing their sensitivity to weak similarities. A new criterion for triggering the extension of word hits, combined with a new heuristic for...
Paper Details
Title
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
Published Date
Sep 1, 1997
Journal
Volume
25
Issue
17
Pages
3389 - 3402
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Notes
History