Oases: robust de novo RNA-seq assembly across the dynamic range of expression levels
Abstract
High-throughput sequencing has made the analysis of new model organisms more affordable. Although assembling a new genome can still be costly and difficult, it is possible to use RNA-seq to sequence mRNA. In the absence of a known genome, it is necessary to assemble these sequences de novo, taking into account possible alternative isoforms and the dynamic range of expression values.We present a software package named Oases designed to...
Paper Details
Title
Oases: robust de novo RNA-seq assembly across the dynamic range of expression levels
Published Date
Feb 24, 2012
Journal
Volume
28
Issue
8
Pages
1086 - 1092
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