Clandestine intracellular delivery of Helicobacter pylori CagA: Guess who's coming to dinner?

See article on page 514.Virtually all persons who are colonized by Helicobacter pylori develop coexisting gastritis, a signature feature of which is the capacity to persist for decades. This is in marked contrast to inflammatory reactions induced by other Gram-negative enteric pathogens, such as Salmonella, that either resolve within days to weeks or progress to eliminate the host. One mechanism through which H. pylori may evade immune clearance...