Original paper
Increased Adipose Protein Carbonylation in Human Obesity
Abstract
Insulin resistance is associated with obesity but mechanisms controlling this relationship in humans are not fully understood. Studies in animal models suggest a linkage between adipose reactive oxygen species (ROS) and insulin resistance. ROS oxidize cellular lipids to produce a variety of lipid hydroperoxides that in turn generate reactive lipid aldehydes that covalently modify cellular proteins in a process termed carbonylation. Mammalian...
Paper Details
Title
Increased Adipose Protein Carbonylation in Human Obesity
Published Date
Sep 1, 2011
Journal
Volume
19
Issue
9
Pages
1735 - 1741
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Notes
History