Oral Docosapentaenoic Acid (22:5n‐3) Is Differentially Incorporated into Phospholipid Pools and Differentially Metabolized to Eicosapentaenoic Acid in Tissues from Young Rats

The present study assessed the effect of oral supplementation with docosapentaenoic acid (DPA, 22:5n-3) on the levels of serum and tissue lipid classes and their fatty acid compositions including individual phospholipid types in rat liver, heart, and kidney. Sprague-Dawley rats received daily oral gavage over 10 days as corn oil without (controls) or with purified DPA in free fatty acid form (21.2 mg/day). The DPA group exhibited significantly...