The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo
Abstract
Formation of neuromuscular synapses requires a series of inductive interactions between growing motor axons and differentiating muscle cells, culminating in the precise juxtaposition of a highly specialized nerve terminal with a complex molecular structure on the postsynaptic muscle surface. The receptors and signaling pathways mediating these inductive interactions are not known. We have generated mice with a targeted disruption of the gene...
Paper Details
Title
The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo
Published Date
May 1, 1996
Journal
Volume
85
Issue
4
Pages
501 - 512
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Notes
History