Alzheimer's disease drug-development pipeline: few candidates, frequent failures

Published on Jan 1, 2014in Alzheimer's Research & Therapy6.142
· DOI :10.1186/alzrt269
Jeffrey L. Cummings135
Estimated H-index: 135
(Cleveland Clinic),
Travis Morstorf2
Estimated H-index: 2
(Touro University Nevada),
Kate Zhong13
Estimated H-index: 13
(Cleveland Clinic)
Introduction Alzheimer’s disease (AD) is increasing in frequency as the global population ages. Five drugs are approved for treatment of AD, including four cholinesterase inhibitors and an N-methyl-D-aspartate (NMDA)-receptor antagonist. We have an urgent need to find new therapies for AD.
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