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The Genome-based Knowledge Management in Cycles model: a complex adaptive systems framework for implementation of genomic applications

Published on Mar 1, 2011in Personalized Medicine1.41
· DOI :10.2217/pme.11.5
Nedal H. Arar18
Estimated H-index: 18
,
Sara J. Knight33
Estimated H-index: 33
+ 1 AuthorsAmalia M Issa10
Estimated H-index: 10
Abstract
The main mission of the Genomic Applications in Practice and Prevention Network™ is to advance collaborative efforts involving partners from across the public health sector to realize the promise of genomics in healthcare and disease prevention. We introduce a new framework that supports the Genomic Applications in Practice and Prevention Network mission and leverages the characteristics of the complex adaptive systems approach. We call this framework the Genome-based Knowledge Management in Cycles model (G-KNOMIC). G-KNOMIC proposes that the collaborative work of multidisciplinary teams utilizing genome-based applications will enhance translating evidence-based genomic findings by creating ongoing knowledge management cycles. Each cycle consists of knowledge synthesis, knowledge evaluation, knowledge implementation and knowledge utilization. Our framework acknowledges that all the elements in the knowledge translation process are interconnected and continuously changing. It also recognizes the importance...
  • References (79)
  • Citations (5)
References79
Newest
#1Francis S. Collins (NIH: National Institutes of Health)H-Index: 178
#1Terry L. Wahls (Roy J. and Lucille A. Carver College of Medicine)H-Index: 13
#2Ika Peleg (OU: University of Oklahoma)H-Index: 1
#1Adam A. Powell (UMN: University of Minnesota)H-Index: 17
#2Diana J. Burgess (UMN: University of Minnesota)H-Index: 35
Last.Melissa R. Partin (UMN: University of Minnesota)H-Index: 23
view all 7 authors...
#1Ahmedin Jemal (ACS: American Cancer Society)H-Index: 106
#2Rebecca L. Siegel (ACS: American Cancer Society)H-Index: 47
Last.Michael J. Thun (ACS: American Cancer Society)H-Index: 126
view all 6 authors...
#1David A. Flockhart (IU: Indiana University)H-Index: 62
#2Todd C. Skaar (IU: Indiana University)H-Index: 34
Last.Anne T. Nguyen (IU: Indiana University)H-Index: 11
view all 5 authors...
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