Original paper
Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients
Abstract
We undertook a randomised controlled trial to assess the efficacy and tolerability of orlistat, a gastrointestinal lipase inhibitor, in promoting weight loss and preventing weight regain in obese patients over a 2-year period.743 patients (body-mass index 28-47 kg/m2), recruited at 15 European centres, entered a 4-week, single-blind, placebo lead-in period on a slightly hypocaloric diet (600 kcal/day deficit). 688 patients who completed the...
Paper Details
Title
Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients
Published Date
Jul 1, 1998
Journal
Volume
352
Issue
9123
Pages
167 - 172
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Notes
History