Gelam Honey Inhibits the Production of Proinflammatory, Mediators NO,PGE2, TNF-α, and IL-6 in Carrageenan-Induced Acute Paw Edema in Rats

Natural honey is well known for its therapeutic value and has been used in traditional medicine of different cultures throughout the world. The aim of this study was to investigate the anti-inflammatory effect of Malaysian Gelam honey in inflammation-induced rats. Paw edema was induced by a subplantar injection of 1% carrageenan into the rat right hind paw. Rats were treated with the nonsteroidal anti-inflammatory drug (NSAID) Indomethacin (10...