Cytosolic phospholipase A2α has a crucial role in the pathogenesis of DSS-induced colitis in mice

Volume: 46, Issue: 2, Pages: 400 - 408
Published: Nov 24, 2015
Abstract
Colitis, an inflammation of the colon, is a well-characterized massive tissue injury. Cytosolic phospholipase A2 α (cPLA2 α) upregulation plays an important role in the development of several inflammatory diseases. The aim of the present study was to define the role of cPLA2 α upregulation in the development of colitis. We used a mouse model of dextran sulfate sodium induced colitis. Immunoblotting analysis showed that cPLA2 α and NF-κB were...
Paper Details
Title
Cytosolic phospholipase A2α has a crucial role in the pathogenesis of DSS-induced colitis in mice
Published Date
Nov 24, 2015
Volume
46
Issue
2
Pages
400 - 408
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