Original paper
The Sequence of the Human Genome
Abstract
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months from 27,271,853 high-quality sequence reads (5.11-fold coverage of the genome) from both ends of plasmid clones made from the DNA of five individuals. Two assembly strategies-a whole-genome assembly and a regional chromosome...
Paper Details
Title
The Sequence of the Human Genome
Published Date
Feb 16, 2001
Journal
Volume
291
Issue
5507
Pages
1304 - 1351
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Notes
History