Review paper
The Gateway Hypothesis of substance abuse: developmental, biological and societal perspectives
Abstract
The Gateway Hypothesis describes how tobacco or alcohol use precedes marijuana and other illicit drug use. We review the epidemiological data, explore the underlying molecular mechanisms in mice and discuss the societal implications of the hypothesis, including the use of e-cigarettes by young people.Our mouse model identifies biological processes underlying the hypothesis, showing that nicotine is a gateway drug that exerts a priming effect on...
Paper Details
Title
The Gateway Hypothesis of substance abuse: developmental, biological and societal perspectives
Published Date
Dec 2, 2014
Journal
Volume
104
Issue
2
Pages
130 - 137
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