ExaBayes: Massively Parallel Bayesian Tree Inference for the Whole-Genome Era

Published on Oct 1, 2014in Molecular Biology and Evolution14.80
· DOI :10.1093/molbev/msu236
Andre J. Aberer15
Estimated H-index: 15
(Heidelberg Institute for Theoretical Studies),
Kassian Kobert7
Estimated H-index: 7
(Heidelberg Institute for Theoretical Studies),
Alexandros Stamatakis50
Estimated H-index: 50
(Heidelberg Institute for Theoretical Studies)
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Modern sequencing technology now allows biologists to collect the entirety of molecular evidence for reconstructing evolutionary trees. We introduce a novel, user-friendly software package engineered for conducting state-of-the-art Bayesian tree inferences on data sets of arbitrary size. Our software introduces a nonblocking parallelization of Metropolis-coupled chains, modifications for efficient analyses of data sets comprising thousands of partitions and memory saving techniques. We report on first experiences with Bayesian inferences at the whole-genome level using the SuperMUC supercomputer and simulated data.
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