Lesion Load of the Corticospinal Tract Predicts Motor Impairment in Chronic Stroke

Previous studies have shown motor impairment after a stroke relates to lesion size and location, but unexplained variability in recovery still exists. In this study, we used lesion-mapping techniques in combination with diffusion tensor imaging to quantitatively test the hypothesis that motor recovery in patients with chronic stroke is inversely related to the proportion of the corticospinal tract (CST) affected by the lesion.We studied 50...