The Structure of the Cerebral Cortex Across Adult Life: Age-Related Patterns of Surface Area, Thickness, and Gyrification

Older adults exhibit global reductions in cortical surface area, but little is known about the regional patterns of reductions or how these relate to other measures of brain structure. This knowledge is critical to understanding the dynamic relationship between different macrostructural properties of the cortex throughout adult life. Here, cortical arealization, local gyrification index (LGI), and cortical thickness were measured vertex wise...