Our Shifting Understanding of Factors Influencing Prostate-Specific Antigen

Prostate cancer continues to be a substantial burden on men’s health with 238590 new cases and 29720 deaths expected in 2013, making it the most commonly diagnosed noncutaneous malignancy and the second leading cause of cancer mortality in men (1). Nonmodifiable risk factors such as age, race, and family history are known to contribute to a man’s risk of developing prostate cancer. In this issue of the Journal, Flynn-Evans and colleagues examine...