ZnCl2 and vitamin C, known as antioxidants, differently potentiate the cytotoxicity of H2O2 in rat thymocytes : Cytometric analysis using forward and side scatters

The ‘antioxidant hypothesis’ proposes that antioxidant nutrients afford protection against chronic diseases by decreasing oxidative damages. The ability of zinc to retard oxidative processes has been recognized for many years. However, the application of ZnCl2 potentiates the cytotoxicity of H2O2. Thus, some antioxidants may be cytotoxic under certain oxidative conditions. Therefore, in this study, the effect of vitamin C, one of antioxidant...