Original paper
Dual utilization of NADPH and NADH cofactors enhances xylitol production in engineeredSaccharomyces cerevisiae
Abstract
Xylitol, a natural sweetener, can be produced by hydrogenation of xylose in hemicelluloses. In microbial processes, utilization of only NADPH cofactor limited commercialization of xylitol biosynthesis. To overcome this drawback, Saccharomyces cerevisiae D452-2 was engineered to express two types of xylose reductase (XR) with either NADPH-dependence or NADH-preference. Engineered S. cerevisiae DWM expressing both the XRs exhibited higher xylitol...
Paper Details
Title
Dual utilization of NADPH and NADH cofactors enhances xylitol production in engineeredSaccharomyces cerevisiae
Published Date
Nov 11, 2015
Journal
Volume
10
Issue
12
Pages
1935 - 1943
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Notes
History