Tumour necrosis factor RECEPTOR activated T cells of patients with systemic sclerosis are deficient in IL-10 expression but promote myofibroblast differentiation via IL-6 and TGF-
Volume: 70, Issue: Suppl 2, Pages: A42 - A43
Published: Feb 22, 2011
Abstract
Background and objectives
Systemic sclerosis (SSc) is an auto-inflammatory multisystem disease leading to fibrosis of the skin and inner organs. T lymphocytes are key effector cells in the affected tissue. The role of lymphocytes in the transition from inflammation to fibrosis is unclear. Previous data suggested a possible pro-fibrotic effect of tumour necrosis factor–receptor (TNF-R) 2.Materials and methods
Skin punch...Paper Details
Title
Tumour necrosis factor RECEPTOR activated T cells of patients with systemic sclerosis are deficient in IL-10 expression but promote myofibroblast differentiation via IL-6 and TGF-
Published Date
Feb 22, 2011
Volume
70
Issue
Suppl 2
Pages
A42 - A43
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Notes
History