Review paper
Oxysterols and atherosclerosis
Abstract
Oxysterols are present in human atherosclerotic plaque and are suggested to play an active role in plaque development. Moreover, the oxysterol:cholesterol ratio in plaque is much higher than in normal tissues or plasma. Oxysterols in plaque are derived both non-enzymically, either from the diet and/or from in vivo oxidation, or (e.g. 27-hydroxycholesterol) are formed enzymically during cholesterol catabolism. While undergoing many of the same...
Paper Details
Title
Oxysterols and atherosclerosis
Published Date
Jan 1, 1999
Journal
Volume
142
Issue
1
Pages
1 - 28
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