Original paper
Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing
Abstract
Paired-tag sequencing approaches are commonly used for the analysis of genome structure. However, mammalian genomes have a complex organization with a variety of repetitive elements that complicate comprehensive genome-wide analyses.Here, we systematically assessed the utility of paired-end and mate-pair (MP) next-generation sequencing libraries with insert sizes ranging from 170 bp to 25 kb, for genome coverage and for improving scaffolding of...
Paper Details
Title
Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing
Published Date
Apr 16, 2013
Journal
Volume
14
Issue
1
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