A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Published on Dec 1, 2012in The Lancet59.10
· DOI :10.1016/S0140-6736(12)61766-8
Stephen S Lim62
Estimated H-index: 62
E. Theo Vos99
Estimated H-index: 99
+ 206 AuthorsMajid Ezzati103
Estimated H-index: 103
(Imperial College London)
Methods We estimated deaths and disability-adjusted life years (DALYs; sum of years lived with disability [YLD] and years of life lost [YLL]) attributable to the independent eff ects of 67 risk factors and clusters of risk factors for 21 regions in 1990 and 2010. W e estimated exposure distributions for each year, region, sex, and age group, and relative risks per unit of exposure by systematically reviewing and synthesising published and unpublished data. We used these estimates, together with estimates of cause-specifi c deaths and DALYs from the Global Burden of Disease Study 2010, to calculate the burden attributable to each risk factor exposure compared with the theoretical-minimum-risk exposure. We incorporated uncertainty in disease burden, relative risks, and exposures into our estimates of attributable burden. Findings In 2010, the three leading risk factors for global disease burden were high blood pressure (7·0% [95% uncertainty interval 6·2–7·7] of global DALYs), tobacco smoking including second-hand smoke (6·3% [5·5–7·0]), and alcohol use (5·5% [5·0–5·9]). In 1990, the leading risks were childhood underweight (7·9% [6·8–9·4]), household air pollution from solid fuels (HAP; 7·0% [5·6–8·3]), and tobacco smoking including second-hand smoke (6·1% [5·4–6·8]). Dietary risk factors and physical inactivity collectively accounted for 10·0% (95% UI 9·2–10·8) of global DALYs in 2010, with the most prominent dietary risks being diets low in fruits and those high in sodium. Several risks that primarily aff ect childhood communicable diseases, including unimproved water and sanitation and childhood micronutrient defi ciencies, fell in rank between 1990 and 2010, with unimproved water
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Published on Jan 1, 2020
Siuly Siuly9
Estimated H-index: 9
(VU: Victoria University, Australia),
Enamul Kabir5
Estimated H-index: 5
(University of Southern Queensland)
+ 2 AuthorsHongbo Kuang
The paper aimed to present a method for the identification of alcoholic brain state using optimum allocation (OA)-based support vector machine (SVM). The OA scheme determines the representative data from a single time window of electroencephalogram (EEG) signals (called brain signal). Several statistical features have been extracted from each time window of EEG signals, and then these features are used to SVM classifier to identify the alcoholic brain state. The experimental results achieved by ...
Published on Jan 1, 2020in Sustainable Cities and Society4.62
Deepti Sharma (PGIMER: Post Graduate Institute of Medical Education and Research), Khaiwal Ravindra26
Estimated H-index: 26
(PGIMER: Post Graduate Institute of Medical Education and Research)
+ 2 AuthorsSuman Mor13
Estimated H-index: 13
(Panjab University, Chandigarh)
Abstract The study aims to identify barriers for cleaner fuel alternatives and willingness to pay in Punjab, India. American Thoracic Society questionnaire was adopted as a study tool having additional questions on fuel subsidy and options, barriers for cleaner fuels choice, including the willingness to pay. Type of cooking fuel choice varies significantly with the monthly income of the family and 67% household uses solid biomass fuel (SBF) as a primary fuel, whereas 21% liquefied petroleum gas ...
Published on Jan 1, 2020in Food Quality and Preference3.68
Thayane C. Lemos (Federal Fluminense University), André Almo (Federal Fluminense University)+ 8 AuthorsNeha Khandpur5
Estimated H-index: 5
(USP: University of São Paulo)
Abstract Front-of-package labels (FOPL) are recommended to reduce consumer intake of ultra-processed food products (UPP). The multiple traffic-light label is one example of FOPL that indicates the content of target nutrients in products by displaying red (high), amber (medium), and / or green (low) color-coding. The red code may implicitly enhance sweetness perception and approach dispositions toward sweet UPP via cross-modal visual-taste interactions. We conducted two experiments to examine the...
Published on Jan 1, 2020
Carolyn Chisadza1
Estimated H-index: 1
(University of Pretoria),
Eleni Yitbarek (University of Pretoria), Nicky Nicholls2
Estimated H-index: 2
(University of Pretoria)
Many countries in sub-Saharan Africa are experiencing an increase in the prevalence of childhood overweight and obesity, even though many countries are still grappling with the persistence of child malnutrition. A quarter of all obese and overweight preschool-aged children live in the region. There is, however, a gap in research on child obesity in African countries, and particularly on how mothers’ empowerment (either through employment or decision-making in the household) might affect this. Th...
Published on Jan 1, 2020in Atmospheric Research4.11
Sheng-Hsiang Wang (NCU: National Central University), Ruo-Ya Hung (NCU: National Central University)+ 5 AuthorsAkinori Takami26
Estimated H-index: 26
(National Institute for Environmental Studies)
Abstract The background PM2.5 concentration represents the combined emissions from natural domestic and foreign sources, which has implications for the maximum effect, in terms of air-quality control, that can be achieved by reducing emissions. However, estimating the background PM2.5 concentration via background monitoring sites for a densely populated region (e.g., Taiwan) has been a challenge. In this study, we compared two statistical methods of estimating the background concentration using ...
Published on Jan 18, 2019in Substance Abuse Treatment Prevention and Policy2.10
Selamawit Zewdu (College of Health Sciences, Bahrain), Charlotte Hanlon28
Estimated H-index: 28
('KCL': King's College London)
+ 2 AuthorsSolomon Teferra11
Estimated H-index: 11
(Harvard University)
Background Although alcohol use disorders contribute a high proportion of population disease burden, the treatment gap is large, especially in low- and middle-income countries. To narrow this gap, contextually relevant evidence is needed to inform service development in low- and middle-income country settings. The aim of this study was to assess the magnitude of the treatment gap for alcohol use disorder, help-seeking behavior, stigma and barriers to care among people with alcohol use disorder i...
Habte Belete3
Estimated H-index: 3
(Bahir Dar University),
Tesfa Mekonen4
Estimated H-index: 4
(Bahir Dar University)
+ 2 AuthorsAsmamaw Getnet2
Estimated H-index: 2
(Debre markos University)
Background Substance miss use and neuro-psychiatric conditions are a growing public health challenges, but 76 to 85% of people with those disorders in low and middle-income countries did not receive treatment. The aim of this study was to see help seeking behavior and determinant factors in residents with problematic substance uses.
Published on Feb 11, 2019in BMC Public Health2.57
Jinhui Li1
Estimated H-index: 1
(NYU: New York University),
Wenbo Guo1
Estimated H-index: 1
(University of Oxford)
+ 9 AuthorsBofu Ning3
Estimated H-index: 3
(CDC: Centers for Disease Control and Prevention)
Background In Xuan Wei, China, the lung cancer mortality rate is rising significantly more than that of the nation overall. However, it remains unclear 1) if improved diagnosis can just partially explain this observation and how other local risk factors may be correlated with the lung cancer mortality rate and 2) how the lung cancer mortality rates differ within Xuan Wei and how these spatiotemporal patterns are linked with local risk factors. To increase etiological knowledge, this study evalua...
Published on Dec 1, 2019in International Journal of Health Geographics2.86
Kenta Okuyama (Shimane University), Takafumi Abe (Shimane University)+ 4 AuthorsToru Nabika25
Estimated H-index: 25
(Shimane University)
Background Neighborhood environments have been regularly associated with the weight status. Although the evidence is mostly limited to adults residing in western urban settings, the weight status of older adults living in rural areas is also assumed to be significantly affected by their neighborhood environments. This study aimed to identify environmental attributes specific to rural areas that could affect the risk of longitudinal weight gain among older adults (≥ 65 years) in Japan.