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Review paper

Origins and Evolution of Antibiotic Resistance

Volume: 74, Issue: 3, Pages: 417 - 433
Published: Aug 30, 2010
Abstract
SUMMARY Antibiotics have always been considered one of the wonder discoveries of the 20th century. This is true, but the real wonder is the rise of antibiotic resistance in hospitals, communities, and the environment concomitant with their use. The extraordinary genetic capacities of microbes have benefitted from man's overuse of antibiotics to exploit every source of resistance genes and every means of horizontal gene transmission to develop...
Figures & Tables
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FIG. 2. Numbers of unique -lactamase enzymes identified since the introduction o...
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FIG. 3. Worldwide distribution of different classes of CTX-M -lactamases (first ...
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FIG. 4. Dissemination of antibiotics and antibiotic resistance within agricultur...
Paper Details
Title
Origins and Evolution of Antibiotic Resistance
Published Date
Aug 30, 2010
Volume
74
Issue
3
Pages
417 - 433
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