Original paper
D Mitochondrial DNA Damage can Promote Atherosclerosis Independently of Reactive Oxygen Species and Correlates with Higher Risk Plaques in Humans
Abstract
Introduction
Mitochondrial DNA (mtDNA) damage occurs in both the vessel wall and in circulating cells in human atherosclerosis. However, whether mtDNA damage promotes atherogenesis or is a consequence of tissue damage is unknown. We assessed the hypothesis that mtDNA damage is present, and can directly promote atherosclerosis and affect plaque composition.Methods
To assess whether mtDNA damage may contribute to atherogenesis...Paper Details
Title
D Mitochondrial DNA Damage can Promote Atherosclerosis Independently of Reactive Oxygen Species and Correlates with Higher Risk Plaques in Humans
Published Date
May 31, 2014
Journal
Volume
100
Issue
Suppl 3
Pages
A128.2 - A129
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Notes
History