Review paper
Identification of rare germline copy number variations over-represented in five human cancer types
Abstract
Copy number variations (CNVs) are increasingly recognized as significant disease susceptibility markers in many complex disorders including cancer. The availability of a large number of chromosomal copy number profiles in both malignant and normal tissues in cancer patients presents an opportunity to characterize not only somatic alterations but also germline CNVs, which may confer increased risk for cancer. We explored the germline CNVs in five...
Paper Details
Title
Identification of rare germline copy number variations over-represented in five human cancer types
Published Date
Feb 3, 2015
Journal
Volume
14
Issue
1
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