Plasmapheresis in severe sepsis and septic shock: a prospective, randomised, controlled trial

To determine the therapeutic efficacy and safety of plasmapheresis in the treatment of patients with severe sepsis and septic shock.Prospective, randomised, clinical trial with a planned, midstudy, interim analysis.Intensive care unit in a university hospital in Archangels, Russia.Consecutive patients with severe sepsis or septic shock.One hundred and six patients were randomised to receive either standard therapy or an add-on treatment with...