Original paper
Elevated extracellular glutamate levels increased the formation of hydroxyl radical in the striatum of anesthetized rat
Abstract
Results from various in vitro experiments have indicated that excitotoxicity and oxidative stress are two interrelated major mechanisms in causing neuronal damage in brain disorders such as cerebral ischemia/reperfusion. Thus, we have conducted experiments to investigate whether in the striatum of anesthetized rats the elevated brain extracellular concentrations of glutamate could increase the formation of hydroxyl radical. Elevation of...
Paper Details
Title
Elevated extracellular glutamate levels increased the formation of hydroxyl radical in the striatum of anesthetized rat
Published Date
Oct 1, 1995
Volume
19
Issue
4
Pages
453 - 459
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Notes
History