Original paper
Injury Is a Major Inducer of Epidermal Innate Immune Responses during Wound Healing
Volume: 130, Issue: 4, Pages: 1167 - 1177
Published: Apr 1, 2010
Abstract
We examined the importance of injury for the epidermal innate immune response in human skin wounds. We found that injury, independent of infiltrating inflammatory cells, generated prominent chemotactic activity toward neutrophils in injured skin because of IL-8 production. Furthermore, injury was a major inducer of the expression of antimicrobial (poly)peptides (AMPs) in skin wounds. In human skin, these injury-induced innate immune responses...
Paper Details
Title
Injury Is a Major Inducer of Epidermal Innate Immune Responses during Wound Healing
Published Date
Apr 1, 2010
Volume
130
Issue
4
Pages
1167 - 1177
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Notes
History