MAPKAP kinases — MKs — two's company, three's a crowd

The MAPK-activated protein kinase (MK) subfamily consists of three structurally related enzymes that function downstream of MAPKs. These kinases are involved in the regulation of actin architecture, cell migration, development, cell-cycle progression and chromatin remodelling as well as mRNA stability and translation. Downstream of mitogen-activated protein kinases (MAPKs), three structurally related MAPK-activated protein kinases (MAPKAPKs or...