Synaptic pathology in alzheimer's disease: Immunological data for markers of synaptic and large dense-core vesicles
Abstract
We have analysed several markers for small synaptic vesicles (synaptin-synaptophysin, p65 and SV2) and large dense-core vesicles (chromogranin A, secretogranin II/chromogranin C) in the brains of patients with Alzheimer's disease, and normal controls by immunoblotting and immunohistochemistry. In comparison to age-matched controls the levels of all three synaptic vesicle markers were decreased in temporal cortex of Alzheimer patients. On the...
Paper Details
Title
Synaptic pathology in alzheimer's disease: Immunological data for markers of synaptic and large dense-core vesicles
Published Date
Jan 1, 1992
Journal
Volume
46
Issue
1
Pages
1 - 8
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