PARP inhibition: PARP1 and beyond
Abstract
Recent findings have thrust poly(ADP-ribose) polymerases (PARPs) into the limelight as potential chemotherapeutic targets. What is known about the structures and functions of the family of PARP enzymes and which questions do we need answered to guide the rational development of PARP inhibitors as anticancer agents? Recent findings have thrust poly(ADP-ribose) polymerases (PARPs) into the limelight as potential chemotherapeutic targets. To...
Paper Details
Title
PARP inhibition: PARP1 and beyond
Published Date
Mar 4, 2010
Journal
Volume
10
Issue
4
Pages
293 - 301
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