Original paper
INTERLEUKIN-15 INTERACTIONS WITH INTERLEUKIN-15 RECEPTOR COMPLEXES: CHARACTERIZATION AND SPECIES SPECIFICITY
Abstract
Interleukin (IL-) 2 and IL-15 share the IL-2 receptor betagamma c subunits (IL-2Rbetagamma c) but have specific, unique alpha receptor subunits. We studied species specificity of human (hu), simian (si), and mouse (mu) IL-15 and found that hu and si IL-15 behaved similarly in all systems investigated. Hu and mu IL-15 bound hu or mu IL-15Ralpha with equal high affinity in the presence or absence of IL-2Rbetagamma c and exhibited similar...
Paper Details
Title
INTERLEUKIN-15 INTERACTIONS WITH INTERLEUKIN-15 RECEPTOR COMPLEXES: CHARACTERIZATION AND SPECIES SPECIFICITY
Published Date
Nov 1, 2002
Journal
Volume
20
Issue
3
Pages
121 - 129
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Notes
History