Endothelial nitric oxide synthase polymorphisms and haplotypes in genetic epidemiology and pharmacogenetics: remarks regarding a lack of association on the risk of myocardial infarction

To the Editor, Arun Kumar et al. [1] have recently reported a clinical study on the possible link between the association of 894G[T and -786T[C NOS3 (endothelial nitric oxide synthase 3) gene polymorphisms and the risk of myocardial infarction (MI) in the South Indian population. They have retrospectively studied a considerable number of patients and healthy controls, but found no association between these NOS3 polymorphisms and MI, even after...