Original paper
Different effects of two cyclic chalcone analogues on cell cycle of Jurkat T cells
Abstract
It has been previously shown that the cyclic chalcone analogues E-2-(4′-methoxybenzylidene)- (2) and E-2-(4′-methylbenzylidene)-1-benzusuberone (3) inhibited proliferation of various murine and human tumor cells. In order to gain new insights into the cytotoxic mechanism of the two compounds detection of apoptosis and necrosis of Jurkat T cells exposed to 2 and 3 were performed by flow cytometry using the Annexin V-FITC and propidium iodide...
Paper Details
Title
Different effects of two cyclic chalcone analogues on cell cycle of Jurkat T cells
Published Date
Dec 1, 2006
Journal
Volume
20
Issue
8
Pages
1354 - 1362
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Notes
History