Original paper
Role for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses
Abstract
Background & Aims As the main detoxifying organ of the body, the liver possesses a remarkable ability to regenerate after toxic injury, tissue resection or viral infection. A growing number of cellular signaling pathways have been implicated in orchestrating the process of liver regeneration. Here we investigated the role of inositol-requiring enzyme-1α (IRE1α), a key signal transducer of the unfolded protein response (UPR), in liver...
Paper Details
Title
Role for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses
Published Date
Mar 1, 2015
Journal
Volume
62
Issue
3
Pages
590 - 598
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Notes
History