Original paper
P and M gene junction is the optimal insertion site in Newcastle disease virus vaccine vector for foreign gene expression
Abstract
Newcastle disease virus (NDV) has been developed as a vector for vaccine and gene therapy purposes. However, the optimal insertion site for foreign gene expression remained to be determined. In the present study, we inserted the green fluorescence protein (GFP) gene into five different intergenic regions of the enterotropic NDV VG/GA vaccine strain using reverse genetics technology. The rescued recombinant viruses retained lentogenic pathotype...
Paper Details
Title
P and M gene junction is the optimal insertion site in Newcastle disease virus vaccine vector for foreign gene expression
Published Date
Jan 1, 2015
Journal
Volume
96
Issue
1
Pages
40 - 45
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Notes
History