Dinuclear bridged biphosphinic and mononuclear cyclopalladated complexes of benzylamines: Synthesis, structural characterization and antitumor activity

Reaction of chloro-bridged dinuclear palladacycles, [Pd2{(C,N)-C6H4CH2NH(R)}2(μ-Cl)2] (R = Et (1a); R = t-Bu (1b)) with pyridine and PPh3 in the 1:2 M ratio at room temperature was used to prepare the mononuclear complexes, [Pd(C,N)-C6H4CH2NH(R)Cl(L)] (R = Et and L = Py (2a); R = t-Bu and L = PPh3 (2b)). Bridged biphosphinic palladacycle, [Pd2(C,N-dmba)2(μ-dppe)(Cl)2] (2c), (where dmba = N,N-dimethylbenzylamine and dppe =...