Original paper
Effect of impeller design on homogeneity, size and strength of pharmaceutical granules produced by high-shear wet granulation
Abstract
Small mixer impeller design is not tailored for granulation because impellers are intended for a wide range of processes. The aim of this research was to evaluate the performances of several impellers to provide guidance on the selection and design for the purposes of granulation. Lactose granules were produced using wet granulation with water as a binder. A Kenwood KM070 mixer was used as a standard apparatus and five impeller designs with...
Paper Details
Title
Effect of impeller design on homogeneity, size and strength of pharmaceutical granules produced by high-shear wet granulation
Published Date
Dec 1, 2015
Journal
Volume
23
Pages
31 - 39
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Notes
History