Anxiety and Stress Responses in Female Oxytocin Deficient Mice

Oxytocin is believed to attenuate the response of the hypothalamic‐pituitary‐adrenal axis to stress and to be anxiolytic. Stressors with a psychological component evoke both central and peripheral secretion of oxytocin in laboratory rodents. Oxytocin gene deletion mice provide a novel way to understand the role of oxytocin in stress and anxiety‐related behaviours. We present our experience with female oxytocin deficient mice that were tested in...