Original paper

Mini-tablets versus pellets as promising multiparticulate modified release delivery systems for highly soluble drugs

Volume: 488, Issue: 1-2, Pages: 86 - 94
Published: Jul 1, 2015
Abstract
Whether mini-tablets (tablets, diameters ≤6 mm) belong to single- or multiple-unit dosage forms is still questionable. Accordingly, Pharmacopoeial evaluation procedures for mini-tablets are lacking. In this study, the aforementioned points were discussed. Moreover, their potential for oral controlled delivery was assessed. The antidepressant venlafaxine hydrochloride (Vx), a highly soluble drug undergoing first pass effect, low bioavailability...
Paper Details
Title
Mini-tablets versus pellets as promising multiparticulate modified release delivery systems for highly soluble drugs
Published Date
Jul 1, 2015
Volume
488
Issue
1-2
Pages
86 - 94
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