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Between 1967 and 1972, there was a serious outbreak of primary pulmonary hypertension in Western Europe.1 The incidence of the disorder among patients seen at major cardiac catheterization centers in Switzerland, Germany, and Austria increased by a factor of 10. This unusual epidemic was traced to the use of an appetite-suppressant drug, aminorex (Menocil), which had been introduced in Europe shortly before. The drug was quickly withdrawn from...