Review paper
The fitness costs of antibiotic resistance mutations
Abstract
Antibiotic resistance is increasing in pathogenic microbial populations and is thus a major threat to public health. The fate of a resistance mutation in pathogen populations is determined in part by its fitness. Mutations that suffer little or no fitness cost are more likely to persist in the absence of antibiotic treatment. In this review, we performed a meta-analysis to investigate the fitness costs associated with single mutational events...
Paper Details
Title
The fitness costs of antibiotic resistance mutations
Published Date
Aug 27, 2014
Journal
Volume
8
Issue
3
Pages
273 - 283
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