Amyloid‐β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

: Increased awareness for a role of oxidative stress in the pathogenesis of Alzheimer's disease has highlighted the issue of whether oxidative damage is a fundamental step in the pathogenesis or instead results from disease‐associated pathology. In vitro experiments support both possibilities: Oxidative stress increases amyloid‐β production, and, conversely, amyloid‐β increases oxidative damage. To address the relationship between amyloid‐β and...