Original paper
Abnormalities in human pluripotent cells due to reprogramming mechanisms
Abstract
Human pluripotent stem cells hold potential for regenerative medicine, but available cell types have significant limitations. Although embryonic stem cells (ES cells) from in vitro fertilized embryos (IVF ES cells) represent the 'gold standard', they are allogeneic to patients. Autologous induced pluripotent stem cells (iPS cells) are prone to epigenetic and transcriptional aberrations. To determine whether such abnormalities are intrinsic to...
Paper Details
Title
Abnormalities in human pluripotent cells due to reprogramming mechanisms
Published Date
Jul 2, 2014
Journal
Volume
511
Issue
7508
Pages
177 - 183
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Notes
History